GenScript Biotech Corporation (Stock Code: 1548.HK) is a global biotechnology group. Founded in 2002, GenScript has an established global presence across North America, Europe, the Greater China, and Asia Pacific. GenScript's businesses encompass four major categories based on its leading gene synthesis technology, including operation as a Life Science CRO, enzyme and synthetic biology products, biologics development and manufacturing, and cell therapy.
GenScript is committed to striving towards its vision of being the most reliable biotech company in the world to make humans and nature healthier through biotechnology.
About ProBio
ProBio proactively provides end-to-end CDMO service from drug discovery to commercialization with proactive strategies, professional solutions and efficient processes in cell and gene therapy (CGT), vaccine, biologics discovery and antibody protein drug to accelerate drug development for customers. ProBio’s total cell and gene therapy solution covers CMC of plasmid and virus for IND filing as well as clinical manufacturing and commercial manufacturing. In terms of plasmid service, ProBio supports the most clinical approvals for CGT drugs including mRNA vaccines, CAR-T in China. It is also the first GMP manufacturing platform to provide in vitro transcription (IVT) template linearized plasmids for mRNA vaccines and has supported several mRNA vaccine global enterprises to obtain clinical approvals. In terms of viral vector service, ProBio has a stable and high-yield viral vector platform.
Job Scope:
We are seeking a highly motivated experienced scientific professional with a multi-disciplinary background in the areas of RNA biology and CRISPR technology focusing on new therapeutics development. This position will involve research and collaboration with scientists and engineers to develop and support new products and services launch.
Location: Redmond, WA
Responsibilities:
- Applying expertise in CRISPR gene editing technology, work with R&D team to develop RNA LNP formulations for customers’ early phase drug development project, and carry out in vitro assays to evaluate the formulations’ performance.
- Design and order required raw materials for projects, Support mRNA and sgRNA LNP formulation design and production.
- Design and carry out RNA/LNP based new drug development early CMC work, include design and carry out stability test for RNA LNP formulations.
- Perform cell-based assay to evaluate gene editing efficiency of candidate’s formulations, and maintain mammalian cell culture for research projects, and downstream cellular DNA extraction and NGS or sanger sequencing assays for data analysis.
- Collaborate with other departments, such as marketing, sales, project management, quality assurance, to resolve technical issues and improve overall service business performance.
- Maintain accurate records of production activities, including inventory levels, equipment maintenances.
- Foster a positive work environment that promotes teamwork, open communication, and continuous improvement.
- Serve as a point of contact for escalations and troubleshooting of production-related issues, ensuring timely resolution and minimal disruption to operations.
Qualifications
- Master’s degree or above Biology, chemical engineer or cell biology field.
- Experience with CRISPR gene editing technology and hands on experimental technics for cell assays and sample processing, data analysis.
- Experience in molecular biology techniques, including primer design, PCR, plasmid construction, sequencing, DNA or RNA purification.
- Proficient in multidisciplinary collaboration, communication, and presentation.
- Problem-solving skills and the ability to make sound decisions under pressure.
- Effective communication skills, both verbal and written, with the ability to interact with diverse teams and stakeholders.
- Proficiency in computer applications, such as Microsoft Office and production management software.
- Knowledge of safety regulations and quality standards relevant to the industry.
- Experience working with mRNA is a plus.
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GenScript USA Inc/ProBio Inc. is a proud equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is the Company's policy to ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protected by law.
GenScript USA Inc./ProBio Inc. maintains a drug-free workplace.
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